For patients with difficult-to-treat seizures in a specific type of epilepsy (temporal lobe epilepsy), a minimally invasive procedure called laser interstitial thermotherapy (LITT) is sometimes used. However, one LITT treatment may not always completely stop seizures. This study looked at patients who had two LITT procedures to see if the second one could improve seizure control. They found that targeting even small remaining problematic areas with a second LITT procedure led to better seizure control in all patients studied. This suggests that repeating this procedure might be a valuable option for patients with persistent seizures, sparing them from more invasive surgeries or less effective treatments. Further research is needed to confirm these findings with a larger group of patients.