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Department of Neurosurgery
March 16, 2026

12-Month Patient-Reported Outcomes Among Urine Toxicology–Identified Substance Users After Elective Spine Surgery: A Prospective Longitudinal Cohort Study

Publication

Singh, Manjot BS*; Shlimak, Anna K. BS*; Rampichini, Margherita BS*; Hasbrouck, Amanda BS*,‡; Clancy, John B. BS*; Chernysh, Alexander A. BS*,‡; Duffy, Maria MBA*,‡; Srinivasan, Anjali BS*; Kanekar, Samika BS*; Bajaj, Ankush MD*; Scarfo, Keith-Austin DO, MS*,‡; Gokaslan, Ziya L. MD*,‡; Leary, Owen P. BS*,‡; Guglielmo, Maria A. MD*,‡

While prior studies have examined the role of opioids, alcohol, and marijuana use on early postoperative outcomes after elective spine surgery, longitudinal studies evaluating the impact of objectively identified preoperative substance use on 12-month outcomes are lacking. 

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12-Month Patient-Reported Outcomes Among Urine Toxicology–Identified Substance Users After Elective Spine Surgery: A Prospective Longitudinal Cohort Study